Research Services Entry Professional

Job Summary:

The Mathew Lab investigates how systemic cytokine signaling and host inflammation shape CD8 T-cell differentiation, antitumor immunity, and responses to cancer immunotherapy. By integrating human clinical studies with mechanistic mouse models, the lab uses high-dimensional flow cytometry, single-cell transcriptomics, multiplex proteomics, and in vivo CRISPR screening to identify cytokine programs that promote durable immune priming or drive terminal T-cell dysfunction.

Key Responsibilities:

• Collect, receive, process, and cryopreserve time-sensitive blood and tissue samples from patients participating in clinical studies.

• Isolate and culture primary immune cells and prepare samples for downstream functional and molecular assays.

• Perform high-dimensional flow-cytometry experiments, including antibody-panel preparation, staining, acquisition, quality control, and analysis.

• Support single-cell transcriptomic, multiplex-proteomic, and CRISPR-screening workflows.

• Assist with mouse models of cancer immunotherapy, including treatment administration, monitoring, tissue collection, and immune profiling.

• Maintain accurate experimental records, clinical-sample inventories, databases, protocols, reagents, and laboratory equipment while following institutional safety and regulatory requirements.

Work Location:

Onsite – this role is expected to work onsite and is located in Aurora, CO.

Why Join Us:

The Department of Immunology and Microbiology at the University of Colorado Anschutz Medical Campus offers a highly collaborative environment for studying fundamental and translational immunology. Team members benefit from close connections among basic scientists, clinicians, and the broader cancer-research community, as well as access to advanced technologies, shared research resources, seminars, and professional-development opportunities.

The Mathew Lab combines ambitious, rigorous science with a supportive and enjoyable team culture. Lab members are expected to be dependable, work thoughtfully, and take ownership of their projects, while receiving mentorship and opportunities to develop new experimental and analytical skills. We value curiosity, open communication, collaboration, and camaraderie—and believe that excellent science and having fun as a team should reinforce one another.

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical: Multiple plan options

• Dental: Multiple plan options

• Additional Insurance: Disability, Life, Vision

• Retirement 401(a) Plan: Employer contributes 10% of your gross pay

• Paid Time Off: Accruals over the year

• Vacation Days: 22/year (maximum accrual 352 hours)

• Sick Days: 15/year (unlimited maximum accrual)

• Holiday Days: 10/year

• Tuition Benefit: Employees have access to this benefit on all CU campuses

• ECO Pass: Reduced rate RTD Bus and light rail service

There are many additional perks & programs with the CU Advantage.

Qualifications:

Minimum Qualifications:

• Bachelor’s degree in biology, molecular biology, chemistry, genetics or related field

• A combination of education and related technical/military/paraprofessional experience may be substituted for a bachelor’s degree on a year for year basis.

Applicants must meet minimum qualifications at the time of hire.

Preferred Qualifications:

• Master’s degree in biology, molecular biology, chemistry, genetics or related field

• Prior experience or background within an experimental or wet lab

Conditions of Employment:

• Applicants must be legally authorized to work in the United States without requiring sponsorship. We are unable to provide work visa sponsorship or employment authorization for this position now or in the future.

Knowledge, Skills and Abilities:

• Knowledge of basic laboratory techniques including safety procedures and techniques

• Ability to communicate effectively, both in writing and orally

• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution

• Outstanding customer service skills

• Demonstrated commitment and leadership ability to advance diversity and inclusion

• Knowledge of basic human anatomy, physiology medical terminology

• Ability to interpret and master complex research protocol information

How to Apply:

For full consideration, please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position

2. Curriculum vitae / Resume

3. Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address

Questions should be directed to: Divij Mathew, divij.mathew@cuanschutz.edu

Screening of Applications Begins:

Applications will be accepted until finalists are identified, but preference will be given to complete applications received by October 1, 2026. Those who do not apply by this date may or may not be considered.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as $47,811 – $58,861.

The above salary range (or hiring range) represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Total Compensation Calculator

Equal Employment Opportunity Statement:

CU is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.

ADA Statement:

The University will provide r