Open Rank Laboratory Science Professional – Pediatric Cardiology Research

Job Summary:

The overall focus of this translational research program is to better understand the unique adaptations governing pathological cardiac remodeling and the progression to heart failure in pediatric patients with complex congenital heart disease, including hypoplastic left heart syndrome and other single ventricle defects. This Laboratory Science Professional will have a key role in conducting a variety of experiments exploring the molecular and functional metabolic changes related to heart failure progression in this population. We utilize human tissue and blood samples in addition to cell culture- and murine- based models to conduct experiments evaluating molecular transcriptomic, proteomic, and functional alterations associated with heart failure progression. This work will be important for the identification and development of drug therapies that improve cardiac function and enhance transplant-free survival in a population with few other options.

Key Responsibilities:

• Cell culture.

• in vivo and ex vivo murine model work.

• Human blood sample processing.

• Molecular and cell biology techniques (RNA, DNA, protein, enzyme activity).

• Mitochondrial metabolic function assessment (Seahorse, Oroboros O2K).

• General laboratory maintenance, including reagent preparation, ordering, organization, and inventory cataloging.

Work Location:

Onsite – This role is expected to work onsite and is in Aurora, Colorado.

Why Join Us:

With an abundance of sunshine and mountains nearby, the Colorado Front Range is the place to be! The University of Colorado Denver, Anschutz Medical Campus as a whole, ranks among the top 20 medical centers in the country. CU Anschutz has top-ranked clinical programs in family medicine and pediatrics, and the basic science and applied health research programs attract more NIH funding than any other university in Colorado. CU-Anschutz is home to the University of Colorado Hospital, The Children’s Hospital of Colorado, and the University of Colorado Schools of Medicine, Nursing, Dentistry, Pharmacy and Pharmaceutical Sciences, and Public Health, providing access to an array of possibilities to improve lives across a spectrum of ages and disease states.

Across several labs at Children’s Hospital Colorado and the Anschutz Medical Campus, teams of researchers, including ours, are investigating the early heart from an ever-growing array of angles, to develop the critical knowledgebase and infrastructure necessary to identify efficacious therapies to improve outcomes in pediatric patients. The Pediatric Heart Tissue and Blood Bank is one of the largest pediatric biobanks in the country and serves as an incredible resource for these translational studies.

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical: Multiple plan options

• Dental: Multiple plan options

• Additional Insurance: Disability, Life, Vision

• Retirement 401(a) Plan: Employer contributes 10% of your gross pay

• Paid Time Off: Accruals over the year

• Vacation Days: 22/year (maximum accrual 352 hours)

• Sick Days: 15/year (unlimited maximum accrual)

• Holiday Days: 10/year

• Tuition Benefit: Employees have access to this benefit on all CU campuses

• ECO Pass: Reduced rate RTD Bus and light rail service

• There are many additional perks & programs with the CU Advantage.

Qualifications:

Minimum Qualifications:

Entry Level:

• Bachelor’s degree in biology, molecular biology, chemistry, genetics, or related field.

  • Substitution: A combination of education and related technical/paraprofessional experience may be substituted for the bachelor’s degree on a year for year basis.

Intermediate Level:

• Bachelor’s degree in biology, molecular biology, chemistry, genetics, or related field

  • Substitution: A combination of education and related technical/paraprofessional experience may be substituted for the bachelor’s degree on a year-for-year basis.

• One (1) year professional-level research experience.

Applicants must meet minimum qualifications at the time of hire.

Condition of Employment:

• Must successfully pass a drug test through Children’s Hospital Colorado.

• Must be willing and able to pass a national criminal background check.

*For questions regarding Children’s Hospital drug testing requirements, please contact Children’s Human Resources at 720-777-8598. Some positions may require testing if access to Children’s Hospital or their systems is needed at any time during employment with the University. If drug testing is required, it will be listed in the job posting.

Preferred Qualifications:

• Master’s degree in biology, molecular biology, chemistry, genetics, or related field.

• Two (2) years of experience in an experimental or wet laboratory.

• Cell culture experience.

• Training in molecular techniques with a good theoretical understanding and experience in interpretation of results.

• Experience using rodent models.

• Laboratory management skills.

Knowledge, Skills, and Abilities:

• Proficient knowledge of basic laboratory techniques, including safety procedures and techniques.

• Ability to communicate effectively, both in writing and orally.

• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution.

• Outstanding customer service skills.

• Demonstrated commitment and leadership ability to advance diversity and inclusion.

• Knowledge of basic human anatomy, physiology, and medical terminology.

• Ability to interpret and master complex research protocol information.

How to Apply:

For full consideration, please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position

2. Curriculum vitae / Resume

3. Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address

Applications are accepted electronically ONLY at www.cu.edu/cu-careers.

Questions should be directed to: Anastacia (Tasha) Garcia, PhD (